Arctic Research Centre

Case Study: Effectively Communicating Modeling Uncertainty to Communities Affected by Cryospheric Hazards – A Look at Interdisciplinary Collaboration Regarding Mendenhall Glacier Lake Outburst Floods in Juneau, Alaska

Cryospheric hazards are natural phenomena that are highly sensitive to climate change impacts and can have devastating impacts on surrounding communities. The rate of glacial change and loss under climate change is unprecedented and can result in more severe glacial hazards globa...

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

ABSTRACT CEP55, a centrosomal protein frequently overexpressed in multiple cancers, is implicated in regulation of genomic instability and PI3K/AKT pathway activation, yet its role in tumor progression and the tumor microenvironment remains incompletely defined. Here, we develope...

Continuous sampling of cerebrospinal fluid from the 3rd ventricle of the hypothalamus to identify accumulating or depleting metabolites during hibernation

Hibernation is a seasonally regulated process dramatically reducing metabolic rate and subsequently core body temperature (Tb). Many hibernators repeatedly cycle between torpor and arousal (T-A cycling) throughout the hibernation season. How these cycles are regulated is still un...