Anyang Hospital of Traditional Chinese Medicine

SHP2 accelerated acute liver injury via modulating TGFβ1/EZH2/BRD4 signaling induced proliferation and fibrosis of HSC

To explore the specific molecular mechanisms by which SHP2 promotes liver injury. Single-cell transcriptomics and bioinformatics analyses were employed for predictive screening. C57BL/6J mice were assigned to normal, model, and model+PHPS1 groups. Liver injury and fibrosis were e...

SEMS bridge to elective laparoscopic surgery versus emergency surgery for obstructive colorectal cancer: a propensity score-matched retrospective cohort study

BACKGROUND: This study compared perioperative recovery and clinical outcomes of patients with obstructive colorectal cancer (OCRC) undergoing self-expandable metallic stent (SEMS) placement followed by elective laparoscopic resection versus emergency surgery. METHODS: Between Jan...

Surgical approaches for screw fixation of calcaneal fractures: a systematic review

To systematically review and summarize the evidence related to different screw configurations in the internal fixation treatment of calcaneal fractures. This systematic review (PROSPERO registration CRD420261389986) employed a comprehensive literature search of PubMed/MEDLINE, Em...