Anqing City Hospital

Multi-omics bioinformatic screening identifies PFDN2 as an obesity-correlated molecular target of triple-negative breast cancer

Abstract Triple-negative breast cancer (TNBC) is characterized by high malignancy, poor prognosis and a lack of specific therapeutic targets. Obesity acts as a major risk factor facilitating TNBC progression, while the molecular features underlying their correlation remain poorly...

A clinical scoring system for the early identification of superinfections in patients with severe fever with thrombocytopenia syndrome: An ambispective multicentre cohort study

Background Superinfection is a major contributor to mortality in patients with severe fever with thrombocytopenia syndrome (SFTS). However, early identification remains challenging because detection of the pathogen causing the superinfection is often delayed. Objective This study...

Analysis and Prediction Study on the Burden of Drug Use Disorders in China from 1990 to 2023: A Systematic Analysis From the Global Burden of Disease Study 2023

INTRODUCTION: Drug use disorders, including amphetamine use disorder (AMD), cocaine use disorder (COD), cannabis use disorder (CAD), opioid use disorder (OPD), and other drug use disorder (OTD), have become a serious global public health issue. However, there are limited systemat...