Animal Husbandry & Veterinary

A novel Alhagi honey polysaccharide-Alum Pickering emulsion adjuvant enhances systemic and mucosal immunogenicity of a BVDV vaccine in calves

Mucosal surfaces are the primary barrier to infection. For pathogens like bovine viral diarrhea virus (BVDV) that invade via the intestinal mucosa, vaccines capable of inducing mucosal immunity are crucial for mounting a comprehensive immune response. In this study, a new assembl...

Multi-layer Cis -molQTLs Reveal Regulatory Architecture and Enhance Heritability Explanation for Complex Traits in Cattle

Abstract Genome-wide association study (GWAS) analyses have identified numerous loci associated with economic traits in cattle. Many of these loci reside in noncoding regions, and the regulatory mechanisms through which they influence complex traits remain poorly understood. Here...

Supplementation with Agrobacterium sp. FN01-Derived Crude Product Dominated by L-β-Galactoglucan Enhances Growth Performance and Nutrient Utilization and Modulates Intestinal Microbiota in Pigs

Polysaccharides are well known for their immunomodulatory properties and gut microbiota-regulating functions; however, their digestive stability and structure-dependent biological mechanisms remain poorly understood. This study investigated the in vitro enzymatic resistance and i...

Integrative GWAS, eQTL, and functional validation identify ZNF280B as a key regulator of growth and carcass traits in Hu sheep

Abstract Hu sheep are a well-known Chinese dual-purpose breed valued for meat production, early sexual maturity, high prolificacy, and adaptability to hot, humid environments. In this study, we combined whole-genome sequencing, GWAS, and eQTL analyses to investigate the genetic b...

Grazing impacts on desert steppe prokaryotic communities: nitrogen speciation, depth stratification, and rhizosphere dynamics

Grazing-induced changes in soil prokaryotic communities are well documented at the surface, yet how grazing reorganizes microbial assembly across soil depth gradients and between bulk soil and rhizosphere compartments remains poorly resolved. This study examines whether prokaryot...

Effects of dietary supplementation with Enterococcus faecalis JM263 on growth performance, antioxidant status, rumen microbiota and metabolism in yaks

Yaks are vital to the ecology and economy of the Qinghai-Xizang Plateau. The unique environmental conditions of this high-altitude region have shaped yaks, leading to significant differences in their evolution from other cattle species. From yak gut contents, we isolated Enteroco...