Animal Husbandry and Veterinary Department

Next-Generation Probiotics: an extensive molecular and clinical review of Live Biotherapeutic Products

The human gastrointestinal tract is a bioreactor of immense complexity, housing over 1014 microorganisms that orchestrate a symphony of metabolic and immunological signals across the host’s systemic landscape. While conventional probiotics have historically relied on a limited re...

Recombinant Lactococcus lactis Expressing IFN-γ Alleviates Viral Enteritis via Microbial and Metabolic Modulation

Abstract Viral enteritis severely impacts the animal industry. Current vaccines and antibiotics have limited efficacy due to virus mutation, drug resistance, and side effects. This study developed an edible lactic acid bacteria (LAB) delivery system, constructing a recombinant st...

Distribution and Catalytic Mechanism of a Novel Carboxylesterase Degrading Multiple Aryloxyphenoxypropionate Herbicides in Bacteria and Archaea

Abstract Aryloxyphenoxypropionate (AOPP), a widely used class of herbicides, pose significant risks to ecosystems and human health. In this study, Bacillus amyloliquefaciens L1 was isolated as a novel degrader, completely degrading 97.42 mg/L cyhalofop-butyl within 12 h via ester...

Population structure and signatures of selection in Horpa sheep

Abstract Horpa sheep, an indigenous sheep breed native to the high-altitude regions of the Xizang Autonomous Region in China, are characterized by distinctive adaptive and economic traits. Whole-genome resequencing and comparative analyses of different sheep populations have been...

Rheum, Scutellaria, and Houttuynia effervescent tablets: a green strategy for controlling Vibrio parahaemolyticus outbreaks in aquaculture

BackgroundThe widespread misuse of antibiotics in aquaculture has led to severe drug resistance, threatening both industry sustainability and food safety. With increasing restrictions on antibiotic use, plant-derived antimicrobials have emerged as eco-friendly alternatives.Purpos...

Preventive Effects of Fermented Yak Milk-Derived Lacticaseibacillus paracasei CD12-1 Against DSS-Induced Colitis in Mice

Ulcerative colitis is a chronic inflammatory bowel disease characterized by mucosal barrier disruption, dysregulated immune responses, and gut microbial imbalance. However, limitations of current therapies highlight the need for safe probiotic interventions. This study evaluated...

Early Compound Nutritional Intervention Improves Hair Follicle Development in Northwest Xizang White Cashmere Goats: An Analysis Based on Skin Multi-Omics

The Northwest Xizang White Cashmere goat has a high global reputation for good goat cashmere germplasm characteristics, and its cashmere industry is the economic pillar of the herdsmen in the northwest plateau of Xizang. Cashmere is produced by the secondary hair follicles of the...

Effects of dietary supplementation with Enterococcus faecalis JM263 on growth performance, antioxidant status, rumen microbiota and metabolism in yaks

Yaks are vital to the ecology and economy of the Qinghai-Xizang Plateau. The unique environmental conditions of this high-altitude region have shaped yaks, leading to significant differences in their evolution from other cattle species. From yak gut contents, we isolated Enteroco...