Andrzej Frycz Modrzewski Krakow University

From Reactive Oxygen Species to Organelle Stress and Innate Immunity in Dry Eye Disease

Dry eye disease (DED) is a complex, multifactorial condition in which oxidative stress is increasingly recognized as a recurrent feature of ocular-surface dysfunction and as a signaling hub linking environmental stress, organelle dysfunction, innate immunity, and regulated cell d...

Differential expression of TGF-β1, TGF-β2, and TGF-β3 across WHO grades in meningioma: convergent evidence from mRNA, methylation, miRNA, and protein analysis

Meningiomas show biological heterogeneity not captured by WHO grading alone. TGF-β signaling has been implicated in meningioma pathobiology, yet a systematic, grade-stratified, isoform-resolved characterization of TGF-β1, TGF-β2, and TGF-β3 across transcriptional, epigenetic, pos...

Crisis Resource Management and Non-Technical Skills Training in Anesthesia: A Narrative Review

Adverse medical events remain a serious concern worldwide; deficiencies in human factors contribute to a large proportion of medical incidents and preventable patient harm.In anesthesiology, where high-risk and complex clinical events are routine, non-technical skills (NTS)-inclu...