Analytical Biosciences (China)

Tiny Droplets, Large Insights: Studying Peptide Aggregationwith Droplet-Based Microfluidics Hyphenated with Ion Mobility MassSpectrometry

Abstract Peptide and protein aggregation are hallmarks of numerous neurodegenerative diseases. However, the structural characterization of oligomeric intermediates remains challenging due to their low abundance, heterogenic nature, and complexity of coinciding and transient react...