Amway (United States)

Competition between root defects and non-uniform properties in governing the tensile deformation behavior of friction stir welds: a finite element analysis

Root defects and non-uniform material properties are two key factors governing the tensile deformation behaviors of friction stir welds, yet the competitive mechanism between these two factors remains unclear. In this study, we propose a finite element model that incorporates bot...

Clinical and mechanistic validation of skin gravitational stretchability as a new metric for skin aging assessment

Maintaining the skin’s dynamic resilience and youthful compliance is crucial to resisting the visible signs of aging, particularly sagging. We modified a previously reported non-invasive tensile method that simulates the gravitational pull on facial skin for the direct measuremen...

A proposed evaluation of new approach methodologies for dermal toxicity assessment of botanicals

Background Botanicals are widely used in topical formulations for cosmetics, hair care, and personal care products, reflecting consumer interest in plant-derived materials. Their complex and variable composition, presents challenges for traditional toxicological approaches develo...

Mulberry Leaf Water Extract Ameliorates Impaired Glucose Tolerance via the Gut Microbiota/SCFAs/AMPKα1 Axis in Adipose Tissue

Background/Objectives: Impaired glucose tolerance (IGT) is a prediabetic condition affecting over 600 million adults worldwide. Mulberry leaf (Morus alba L.) has shown antidiabetic potential, but whether adipose AMPKα1 is required for its effects remains unclear. This study aimed...