Amrita Institute of Medical Sciences and Research Centre

Timing and trajectory of acute kidney injury predict mortality in alcohol-associated hepatitis: A multinational cohort study.

BACKGROUND: Acute kidney injury (AKI) is common in alcohol-associated hepatitis (AH) and associated with poor outcomes, yet the prognostic implications of AKI timing and early renal trajectory remain unclear. METHODS: In this prospective multicenter cohort from the Global AlcHep...

Clinicopathological profile and prognostic subgrouping of mantle cell lymphomas: A six-year retrospective study from a tertiary care center in Kerala

ABSTRACT Background: Mantle cell lymphoma (MCL) is a rare mature B-cell non-Hodgkin lymphoma that is known to exhibit heterogeneous biological behavior and variable clinical outcomes. Ki-67 proliferation index, blastoid morphology, and p53 expression are important prognostic mark...

TAPESTRY study: impact of prior transurethral resection of the prostate on outcomes after robot-assisted radical prostatectomy: a propensity score-matched cohort study

Abstract Prior transurethral resection of the prostate (TURP) may distort bladder neck and apical anatomy and complicate robot-assisted radical prostatectomy (RARP). Its effect on anastomotic recovery and oncological control remains controversial. To evaluate perioperative, anast...

Consensus recommendations for standardising ILD multidisciplinary discussions in India

Abstract Background Interstitial lung diseases (ILDs) are complex, heterogeneous disorders that require accurate diagnosis and coordinated care. Multidisciplinary discussions (MDMs) are considered the gold standard for ILD management; however, in India, the implementation of stru...

Efficacy of a single dose of postoperative intravenous iron on erythropoietic recovery for Return to Intended Oncological Therapy in patients with head and neck cancer: A randomized controlled trial

Abstract Background and Aims: Perioperative anemia is a critical barrier to Return to Intended Oncological Therapy (RIOT) in head and neck cancer (HNC) patients. Surgery-induced systemic inflammation triggers a hepcidin surge, causing functional iron deficiency that limits erythr...

The impact and evolution of environmental/occupational, behavioural, and metabolic risk factors on CVD burdens in the Asia–Pacific region from 1990 to 2023: a secondary analysis of the Global Burden of Disease Study 2023

Background Understanding epidemiological trends of the cardiovascular risk factors is integral in designing effective countermeasures in tackling cardiovascular diseases (CVD) in the Asia–Pacific. The study aims to examine the cardiovascular risk factor burden in the Asia–Pacific...

Artificial intelligence-enabled insights into dietary modifications driving the progression from metabolic dysfunction-associated steatotic liver disease to hepatocellular carcinoma

Dietary patterns represent a major modifiable risk factor contributing to metabolic dysfunction-associated steatotic liver disease (MASLD), which can lead to insulin resistance, inflammation, gut dysfunction and hepatic steatosis. Diet-induced animal models have become essential...

Socio cultural determinants of dietary and health behaviours among women of reproductive age in rural India

A qualitative study was conducted to understand the sociocultural dynamics influencing the food security of women of reproductive age in Tantichira, a rural tribal village of Odisha, India—a representation of developing countries. Eastern societies worldwide were found to have fo...

Drug stock-outs in HIV, tuberculosis, and malaria programs: a systematic review

Background Stock-outs of antiretroviral, anti-tuberculosis, and anti-malarial medicines remain a major challenge in low- and middle-income countries, affecting both health systems and patient outcomes. This systematic review aimed to synthesize evidence on the causes, consequence...