Amgen (United States)

Osteoporotic fracture, diagnostic activity, and treatment in patients with gout

BACKGROUND: Patients with gout may be at high risk for developing osteoporosis and osteoporotic fractures, but osteoporosis may be under-recognized and inadequately managed for patients with gout. We aimed to describe osteoporotic fractures and diagnosis, DXA utilization, and bon...

FullMS2Former:A Transformer Model for Near-CompletePrediction of Peptide Tandem Mass Spectra

Abstract Accurate prediction of peptide tandem mass spectra is essential for confident peptide identification. Existing deep learning models achieve high similarity to experimental spectra but remain constrained by fixed fragment dictionaries of common fragment ions, limiting the...