American Standard (United States)

Effects of a Mushroom-Based β-Glucan and Bovine Colostrum Blend on the Gastrointestinal Health and Immune Function of Healthy Adult Dogs

Abstract Mushroom-derived β-glucans and bovine colostrum have potential roles in modulating gut health and immune function, but limited data are available regarding their effects on the gut microbiome, microbial metabolites, and immune responsiveness in adult dogs. Twenty healthy...

Evaluating a smartphone intervention to improve HIV prevention and care outcomes: results from the HealthMPowerment national randomized controlled trial

HealthMPowerment (HMP) is a digital intervention designed to improve HIV-related outcomes among young Black and Latinx men who have sex with men (YBLMSM) and transgender women (TW). We conducted a 12-month randomized controlled trial to evaluate HMP’s impact on routine HIV testin...

What Does MLX 4-bit Cost? A Controlled Audit of Quantization for Code Generation on Apple Silicon

Controlled measurement of what MLX default 4-bit quantization costs five code models on HumanEval+ and MBPP+ against bf16 baselines converted from the same weights. Pooled: 220 discordant pairs favour bf16 against 125 (McNemar p < 1e-6); the loss shrinks with model size at +0.52...

TopK Sparse Autoencoders Across Three Model Architectures: Dictionary Collapse, Dense-Feature Degeneracy, and the Limits of Activation-Pattern Feature Matching

TopK SAEs trained at matched sparsity and dictionary size on Llama-3.2-3B, Mistral-7B-v0.3 and Qwen2.5-3B. Reports abrupt dictionary collapse with partial recovery, dense-feature degeneracy invalidating frequency-based feature selection, and a null cross-architecture matching res...

Efficient Mechanistic Circuit Analysis of Open-Weight LLMs on Apple Silicon

Replication and extension of the GPT-2 Small IOI circuit analysis on Llama-3.2-3B and Pythia-1.4B using an MLX activation-patching harness on a single Apple Silicon machine. Circuits are faithful on the standard single-template dataset (F=0.663 and 0.854) but collapse on a 15-tem...

Distributed Mechanistic Interpretability at Scale: Activation Streaming, Split-Layer Inference, and Distributed Sparse Autoencoder Training

ActStream: a two-node system that splits inference and analysis, streams intermediate activations over a binary wire protocol, and trains sparse autoencoders without staging activations to disk. Thunderbolt measured at 2.150 GB/s, 86% of negotiated rate and 26x the LAN path, with...