American Pharmacists Association

Fabrication and statistical optimisation of Nifedipine-loaded alginate nanoparticles using honey as a natural stabilizer

Nifedipine (NF) is widely used to manage hypertension and angina. However, its poor aqueous solubility limits oral delivery, warranting sustained, pH-responsive release systems. This study fabricated and optimised NF-loaded alginate nanoparticles (NF-loaded Alg-NPs) using honey a...

DEVELOPMENT OF POLYHERBAL SUGAR-FREE CHOCOLATE CUBES FOR STRESS MANAGEMENT

Chocolate is a highly acceptable food matrix for the delivery of bioactive ingredients, but its conventional sugar content limits its suitability for health-oriented formulations. Sugar-free dark chocolate enriched with botanicals therefore represents a promising functional confe...

DEVELOPMENT OF POLYHERBAL SUGAR-FREE CHOCOLATE CUBES FOR STRESS MANAGEMENT

Chocolate is a highly acceptable food matrix for the delivery of bioactive ingredients, but its conventional sugar content limits its suitability for health-oriented formulations. Sugar-free dark chocolate enriched with botanicals therefore represents a promising functional confe...

Spatially-integrated Ancestry Polygenic Risk Mapping for Diabetes: A Geographic-adjusted Genetic Scoring Framework

Abstract Background: Conventional polygenic risk scores (PRSs) often fail to capture geographic and ancestry-specific variation, limiting their predictive accuracy in admixed and globally diverse populations. This study aims to develop a spatially-aware PRS (SA-PRS) framework tha...