Alzheimer's Association

Hemispheric Asymmetry of Neuroimaging Biomarkers in Early Onset Alzheimer's Disease: Clinical and Cognitive Outcomes

Objective Individuals diagnosed with Alzheimer's disease (AD) often exhibit amyloid, tau, and atrophy predominantly in the left or right hemisphere, but group‐level analyses typically ignore inter‐individual variability and changing asymmetry patterns when averaging data across p...

The use of real‐world data in health services research for dementia care: A scoping review

Abstract Health services research (HSR) is critical to informing dementia care and often relies on real‐world data (RWD); however, RWD use in HSR has not been systematically mapped in the United States. Following previous researchers and Preferred Reporting Items for Systematic R...

Organizing healthcare delivery in the era of disease-modifying therapies for Alzheimer’s Disease: an Italian RAND/UCLA consensus

BACKGROUND: Alzheimer's disease (AD) poses a growing clinical and organizational challenge, requiring coordinated, multidisciplinary care models. In Italy, significant regional variability in resources and access to diagnostic services persists, while the implementation of commun...

Mediating effect of pro-inflammatory cytokines in the association between depression, anxiety, and cardiometabolic disorders in a multiethnic US population

Abstract Neuroinflammation is associated with depression and anxiety risk, both of which demonstrate a bilateral relationship with cardiometabolic disorders. Systemic inflammation was also commonly described in patients with cardiometabolic disorders. It is, thus, unclear whether...

Lessons From the Communication Bridge Trials: Advancing Meaningful Dyadic Interventions Toward Implementation

Purpose: This review describes the historical motivations, development, and evolution of the Communication Bridge (CB) research program, which is designed to maximize quality of life and minimize burden for individuals living with dementia and their communication partners. The CB...