Allegheny Health Network

Colchicine for cardiovascular secondary prevention: evidence from recent trials and meta-analyses

PURPOSE OF REVIEW: Residual inflammatory risk remains an important driver of recurrent vascular events despite contemporary lipid-lowering and antithrombotic therapies. Low-dose colchicine is the first widely available anti-inflammatory therapy to be incorporated into contemporar...

Hepatic Encephalopathy in Critical Care

Hepatic encephalopathy (HE) is a complex neurocognitive disorder stemming from liver dysfunction, ranging from subtle cognitive impairments to profound coma. It develops when the liver's detoxification capacity is compromised, leading to an accumulation of neurotoxins like ammoni...