All India Institute of Medical Sciences Rishikesh

Development of diagnostic reference levels and acceptable quality dose for computed tomography in an Indian tertiary care center

Background Computed tomography (CT) contributes substantially to medical radiation exposure, making diagnostic reference levels (DRLs) important for dose optimization. This study aimed to establish preliminary institutional DRLs and evaluate acceptable quality dose (AQD) at an In...

Association of social factors with physical frailty in community dwelling older adults: a cross-sectional study in Northern India

Frailty is a multifaceted geriatric syndrome encompassing physical, social, cognitive, and psychological components, with social factors gaining prominence as critical determinants. Social isolation, lack of support, and reduced participation are linked to adverse outcomes like i...

Multiple bee stings leading to a delayed fatal coronary event with probable Kounis syndrome: a case report

Kounis syndrome—an acute coronary syndrome occurring in the setting of allergic or hypersensitivity reactions—remains an under-recognised clinical entity. In many cases, the diagnosis is largely probabilistic, particularly in the absence of confirmatory evidence such as mast-cell...

Disseminated histoplasmosis presenting with polymorphic mucocutaneous lesions in a renal transplant recipient

Disseminated histoplasmosis is an opportunistic fungal infection caused by Histoplasma capsulatum that commonly affects immunocompromised individuals. Cutaneous manifestations are polymorphic and may mimic several dermatological disorders, leading to diagnostic difficulty. We rep...

Left Atrial Strain Impairment in Embolic Stroke of Undetermined Source: A Systematic Review and Meta-Analysis

Embolic stroke of undetermined source (ESUS) accounts for approximately one-third of all ischemic strokes. Atrial cardiomyopathy, independent of paroxysmal atrial fibrillation, is an increasingly recognized embolic substrate. Left atrial (LA) strain assessed by speckle-tracking e...

Unidirectional barbed versus single layer conventional suture for vaginal cuff closure in robotic hysterectomy: retrospective single-center study

Objective: Successful vaginal cuff suturing remains a major challenge in robotic hysterectomy. This study compared the vault closure time by using Vicryl (polyglactin 910) and barbed (V-Loc) sutures. Material and Methods: This retrospective study included patients undergoing robo...

Mitophagy and Noncoding RNA Regulation in Type 2 Diabetes Mellitus: Molecular Mechanisms, Tissue-Specific Evidence and Translational Perspective

Despite significant therapeutic advances, T2DM remains a global public health challenge that leads to multiple complications, including cardiovascular, renal, hepatic, and neurodegenerative disorders. Mitochondrial dysfunction and impaired mitophagy remain fundamental, yet incomp...

Primary orbital hydatid cyst presenting as painless proptosis in an adolescent: a case report with imaging correlation

Abstract Background Echinococcus granulosus is a parasitic cestode responsible for hydatid disease affecting humans. Hydatid disease may involve multiple organs, with the liver and lungs being the most commonly affected. However, orbital involvement is exceptionally rare, account...

Predictive patient characteristics for chemotherapy-induced nausea and vomiting in solid organ cancers: an observational study from a tertiary care setting

Chemotherapy-induced nausea and vomiting (CINV) persists in a substantial proportion of patients despite guideline-based antiemetic prophylaxis. Current preventive strategies largely emphasize chemotherapy-related risk, with limited consideration of patient-specific factors. This...