All India Institute of Medical Sciences Jodhpur

Bone health and hypogonadism in acquired immunodeficiency syndrome wasting syndrome: Methodological considerations

Dear Editor

Effectiveness of Community-Based Educational Interventions in Reducing Blood Pressure in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis

Abstract Blood pressure (BP) is a major health burden in low- and middle-income countries (LMICs), where effective control remains a challenge. Community-based education may help improve outcomes in these settings. To systematically review and assess the impact of community-based...

Comprehensive genetic counseling in pediatric cancer: Overcoming challenges and setting standards

Comprehensive genetic counseling in pediatric oncology is a complex and evolving field with unique challenges and considerations. There is a need for specialized genetic counseling services, particularly in cancer predisposition surveillance. The article emphasizes the crucial ro...

Burst abdomen in a case of fatal high‐voltage electrocution: A rare entity

Abstract High‐voltage electrocution (>1000 volts) commonly presents with flash burns, flame burns, and injuries due to the entry and exit of current in the body. Sometimes, unusual injuries are encountered in high‐voltage electrocution. A burst abdomen with perforation of the gas...

Prevalence of dyslipidaemia in patients diagnosed with de novo adhesive capsulitis: A cross-sectional study

Background Adhesive capsulitis is an idiopathic condition characterized by painful restriction of shoulder movements, with diabetes mellitus identified as a commonly associated factor. Dyslipidaemia has been suggested as a potential contributing factor. Additionally, elevated inf...

Endothelial Plasticity as a Continuum in the Tumor Microenvironment

The tumor microenvironment (TME) is a dynamic and complex ecosystem in which endothelial cells (ECs) play a central role beyond their traditional function as passive vascular conduits. Increasing evidence indicates that tumor-associated endothelial cells (TECs) undergo profound p...

Bridging epidemiological gaps in rare diseases: Overcoming systemic and socio-economic challenges through integrated solutions

Rare diseases collectively affect over 300 million individuals globally, yet their epidemiology remains inadequately characterised, particularly in low- and middle-income countries. In India, epidemiological gaps arise from fragmented data systems, diagnostic odyssey, and limited...

Infection profile and risk factors for adverse outcomes in children with febrile neutropenia: a single-center study from Northwestern India

= 13). Profound neutropenia at presentation was a predictor of prolonged hospital stay. CRP was a predictor of mortality and the need for intensive care. Procalcitonin was a predictor of all adverse outcomes explored in the study-bloodstream infection, mortality, need for intensi...

Psychiatric morbidity and coping in caregivers of patients with substance use disorder

Background Caregivers of patients with substance use disorders often experience psychological distress, but psychiatric morbidity and coping, including religious coping, remain under-studied in Indian treatment settingsObjective To assess psychiatric morbidity, coping strategies,...

Quality and concordance of international paediatric sepsis guidelines: a cross-sectional appraisal from the SENTINEL International study

Objectives To evaluate the methodological quality of hospital-specific paediatric sepsis clinical practice guidelines (CPGs) from sites participating in an international study using the Appraisal of Guidelines for Research and Evaluation II (AGREE II) tool and to assess the consi...

Genome-wide association analysis of endometriosis in Indian women supports shared genetic susceptibility and suggestive population specific signals

Endometriosis is an estrogen-dependent, chronic gynaecological disorder affecting approximately 10% of women of reproductive age and is associated with pelvic pain, infertility, and reduced quality of life. Genetic studies indicate substantial heritability, yet genome-wide associ...

Therapeutic Plasma Exchange in Neuromyelitis Optica Spectrum Disorder: Real‐World Clinical Outcomes and Safety From a Tertiary Care Center in Northwest India

BACKGROUND AND OBJECTIVES: Neuromyelitis Optica Spectrum Disorder (NMOSD) is a severe autoimmune demyelinating disorder of the central nervous system characterized by relapsing attacks that can result in permanent neurological disability. Therapeutic Plasma Exchange (TPE) is reco...

Peroral Endoscopic Cardial Constriction with Band ligation for Gastroesophageal Reflux Disease: A Prospective Pilot Study

Background- Limited retrospective data suggest PECC-b (Peroral endoscopic cardial constriction with band ligation) as feasible, safe, and effective treatment for GERD. We performed prospective study to assess efficacy and safety of PECC-b for treatment of GERD. Methods We prospec...

Fatal infantile encephalopathy due to NAXE variant: Navigating the Metabolic-Mitochondrial overlap in NAXE gene

Abstract Background Progressive Encephalopathy with Brain Edema and/or Leukoencephalopathy-1 (PEBEL-1) is a rare, rapidly progressive, and often fatal infantile neurometabolic disorder caused by pathogenic variants in the NAXE gene. Loss of NAXE impairs the NAD(P)HX repair pathwa...

Histoplasmosis in India: a systematic review of reported cases

BACKGROUND: Histoplasmosis is a systemic fungal infection caused by Histoplasma capsulatum and is increasingly recognised in India, but its epidemiology, clinical spectrum, diagnosis, treatment, and outcomes remain poorly characterised. We conducted a systematic review of reporte...

Comparative Evaluation of the Efficacy of C-MAC™, McGrath MAC™ Videolaryngoscopes, and the Direct Miller Laryngoscope for Neonatal Intubation under General Anesthesia

BACKGROUND: Neonatal endotracheal intubation remains technically challenging due to small airway dimensions and limited glottic visualization. Identifying the most effective device and technique to secure the airway is crucial. Video laryngoscopes (VLs) have been introduced to en...

Effect of nurse-led respiratory muscle training on functional capacity and respiratory muscle strength in patients with haemodialysis: a quasi-experimental study

Abstract Introduction Chronic kidney disease (CKD) is a global health concern, often diagnosed late, particularly in India. Hemodialysis (HD), the most common treatment, impacts quality of life and can lead to impaired respiratory functions. Spirometry parameters (FVC, FEV₁) asse...

Dedifferentiated Chondrosarcoma of the Distal Femur: Diagnostic Challenges and Limb Salvage with Double-Barrel Fibular Graft Reconstruction

Dedifferentiated chondrosarcoma (DCS) is a rare and aggressive variant of chondrosarcoma characterized by a biphasic histological pattern and poor prognosis. We report a case of DCS arising in the distal femur of a 48-year-old woman who presented with progressive pain and swellin...