All India Institute of Medical Sciences Jodhpur

Therapeutic Plasma Exchange in Neuromyelitis Optica Spectrum Disorder: Real‐World Clinical Outcomes and Safety From a Tertiary Care Center in Northwest India

BACKGROUND AND OBJECTIVES: Neuromyelitis Optica Spectrum Disorder (NMOSD) is a severe autoimmune demyelinating disorder of the central nervous system characterized by relapsing attacks that can result in permanent neurological disability. Therapeutic Plasma Exchange (TPE) is reco...

Peroral Endoscopic Cardial Constriction with Band ligation for Gastroesophageal Reflux Disease: A Prospective Pilot Study

Background- Limited retrospective data suggest PECC-b (Peroral endoscopic cardial constriction with band ligation) as feasible, safe, and effective treatment for GERD. We performed prospective study to assess efficacy and safety of PECC-b for treatment of GERD. Methods We prospec...

Histoplasmosis in India: a systematic review of reported cases

BACKGROUND: Histoplasmosis is a systemic fungal infection caused by Histoplasma capsulatum and is increasingly recognised in India, but its epidemiology, clinical spectrum, diagnosis, treatment, and outcomes remain poorly characterised. We conducted a systematic review of reporte...

Fatal infantile encephalopathy due to NAXE variant: Navigating the Metabolic-Mitochondrial overlap in NAXE gene

Abstract Background Progressive Encephalopathy with Brain Edema and/or Leukoencephalopathy-1 (PEBEL-1) is a rare, rapidly progressive, and often fatal infantile neurometabolic disorder caused by pathogenic variants in the NAXE gene. Loss of NAXE impairs the NAD(P)HX repair pathwa...

Comparative Evaluation of the Efficacy of C-MAC™, McGrath MAC™ Videolaryngoscopes, and the Direct Miller Laryngoscope for Neonatal Intubation under General Anesthesia

BACKGROUND: Neonatal endotracheal intubation remains technically challenging due to small airway dimensions and limited glottic visualization. Identifying the most effective device and technique to secure the airway is crucial. Video laryngoscopes (VLs) have been introduced to en...

Effect of nurse-led respiratory muscle training on functional capacity and respiratory muscle strength in patients with haemodialysis: a quasi-experimental study

Abstract Introduction Chronic kidney disease (CKD) is a global health concern, often diagnosed late, particularly in India. Hemodialysis (HD), the most common treatment, impacts quality of life and can lead to impaired respiratory functions. Spirometry parameters (FVC, FEV₁) asse...

Dedifferentiated Chondrosarcoma of the Distal Femur: Diagnostic Challenges and Limb Salvage with Double-Barrel Fibular Graft Reconstruction

Dedifferentiated chondrosarcoma (DCS) is a rare and aggressive variant of chondrosarcoma characterized by a biphasic histological pattern and poor prognosis. We report a case of DCS arising in the distal femur of a 48-year-old woman who presented with progressive pain and swellin...