Alexandria National University

Macro-scale cortical thickness homogeneity in Alzheimer’s disease evaluated across 11,382 structural MRI scans from two independent cohorts

Alzheimer’s disease (AD) is characterized by progressive, regionally heterogeneous cortical atrophy. Whether whole-brain cortical thickness homogeneity serves as an informative macro-scale marker of this structural disruption remains unclear. This study evaluated cortical thickne...