Albany Medical Center Hospital

Advances in Diagnostic Testing for Eosinophilic Esophagitis: Current Approaches, Limitations, and Emerging Technologies

Background/Objectives: Eosinophilic esophagitis (EoE) is a chronic disease of the esophagus caused by an abnormal type 2 (Th2) immune response. It is a leading cause of dysphagia in both pediatric and adult populations. Endoscopy with biopsy remains the standard approach for diag...

Transcriptional regulation and function of GPR18 in macrophage subtype specification

Resolution of inflammation is mediated in part by agonists that engage immune cells to dampen inflammatory signaling, promote phagocytic functions, and facilitate tissue repair. G protein–coupled receptor 18 (GPR18) has emerged as an important proresolving receptor that is activa...

Patient Risk Factors for Incidental Pathology After Uterovaginal Surgery for Apical Prolapse: Systematic Review and Global Expert Consensus Statements

Abstract Introduction and Hypothesis Uterus preservation is increasingly used for uterovaginal prolapse (U-POP) repair despite ongoing concerns regarding future uterine, cervical, and adnexal pathology. We evaluated incidental pathology rates, associated risk factors, and created...

Comparative Efficacy of Embolic Agents for Single-Session Meningeal Artery Embolization and Surgical Evacuation: Evaluating Liquids, Particles, and Adjunct Coils

BACKGROUND AND OBJECTIVES: Single-session middle meningeal artery embolization (MMAE) combined with surgical evacuation is an emerging strategy for management of patients with chronic subdural hematoma (cSDH). However, comparative outcome data based on embolic material selection...

Lipidomic Profiling Reveals Stage-Associated Triglyceride Accumulation in Macrophages in a Mouse Model of Ovarian Cancer

Background/Objectives: Tumor-associated macrophages (TAMs) are critical mediators for immunosuppressive ovarian tumor microenvironments. However, the lipid metabolic features of macrophages at different stages of ovarian tumor development remain poorly understood. Methods: Here,...

Proximity Is Not Access: Geographic Distance and Chemotherapy Receipt for Colon Cancer Requiring Surgery

Background Access to health care facilities presents an obstacle to receiving appropriate cancer treatment. This retrospective cohort study analyzes how access to care by geographic distance and patient demographics affect receipt of chemotherapy in colon cancer patients requirin...

Superlarge-Bore Versus Large-Bore Aspiration Catheters in Mechanical Thrombectomy: A Multicenter Propensity-Matched Analysis

BACKGROUND AND OBJECTIVES: Aspiration catheters are an integral component of mechanical thrombectomy for acute ischemic stroke (AIS). Following early series demonstrating increasing procedural efficiency and improved outcomes with use of large-bore (LB) aspiration catheters, ther...

Early-Onset Systemic Lupus Erythematosus with Discoid Rash and Chondritis

Abstract Juvenile Systemic Lupus Erythematosus (jSLE) is a rare disorder that presents with greater severity compared to adult Systemic Lupus Erythematosus. It typically manifests in adolescent females with constitutional symptoms, multisystem involvement, and a malar rash. In th...

Study protocol for first national vasa previa perinatal registry

Vasa previa is a rare but potentially catastrophic obstetric condition characterized by unprotected fetal blood vessels over or adjacent to the internal cervical os. Although advances in prenatal ultrasound have dramatically improved neonatal survival through planned cesarean del...