Agricultural Genomics Institute at Shenzhen

AR: An Artificial Intelligence‐Driven Fluorescent Reporter System for Gene Editing Evaluation

ABSTRACT Accurate and scalable evaluation of gene‐editing efficiency is crucial for the development of novel editing tools. However, conventional methods are laborious, costly, and low‐throughput. Here, we developed an artificial intelligence (AI)‐driven fluorescent reporter (AR)...

Odorant Receptors Mediating Benzaldehyde Detection in Mythimna separata: Functional Identification and Ligand Selectivity

Benzaldehyde (BA) is a ubiquitous aromatic volatile produced by both plants and insects. In Mythimna separata, it also serves as a male-emitted pheromonal signal that mediates male–male competition by antagonizing the pheromone receptor MsepPR3 and disrupting the perception of th...

Winter Dietary Composition of Black Francolin (Francolinus francolinus) in Totali Public Game Reserve, Pakistan

The winter diet of Black Francolin (Francolinus francolinus) is poorly documented in Totali Public Game Reserve, Pakistan. We examined crop contents from 24 legally harvested birds (14 males and 10 females) collected during 2022–2024. Thirty-three identifiable food taxa were reco...

Integrated lncRNA and mRNA Transcriptome Analysis Reveals Candidate Regulatory Networks Associated with Postnatal Longissimus Dorsi Muscle Development in Hanper Sheep

Skeletal muscle development is a key determinant of meat production and meat-quality traits in sheep, but the coordinated long non-coding RNA (lncRNA) and messenger RNA (mRNA) co-expression landscape underlying postnatal muscle development in Hanper sheep remains unclear. In this...

Pan‐genomic analysis of alternative polyadenylation reveals a 3′UTR remodeling regulatory layer controlling salt tolerance in rice

Alternative polyadenylation (APA) generates mRNA isoforms with variable 3'UTR lengths, yet its genetic basis and functional significance at the population level remain unexplored in plants. Here, we present the population-level APA landscape and the APA quantitative trait loci (3...

Rhizosphere microbiome-dependent metabolic reprogramming enhances potato salt tolerance in saline soils

Soil salinization is increasing globally, causing yield losses, especially in irrigated agriculture. Rhizosphere microorganisms can improve plant salt tolerance, but evidence in potato remains limited. In this study, rhizosphere microbial community diversity and structure differe...

Melanomacrophages exhibit FDC-like features: aquatic reovirus induces melanomacrophage death to suppress antibody responses

Genotype II grass carp reovirus (GCRV-II)-caused grass carp hemorrhagic disease severely restricts aquaculture, yet its adaptive immune evasion mechanism remains unclear. In mammals, follicular dendritic cells (FDCs) act as the core antigen-presenting cells that drive germinal ce...

Integrative Multi‐Omics Analysis Identifies Candidate MicroRNA Regulatory Networks Associated With High‐Altitude Adaptation in Tibetan Pigs

MicroRNAs (miRNAs) are key posttranscriptional regulators of gene expression and play important roles in physiological responses to hypoxia, particularly in the cardiovascular system. However, the regulatory roles of miRNAs in cardiopulmonary tissues during high-altitude adaptati...

Dietary Fermented Mulberry Leaf Triggers Dose-Dependent Changes in Growth, Antioxidant Immune Status and Intestinal Microecology of Amur Sturgeon (Acipenser schrenckii)

Mulberry leaf is a promising sustainable plant-based feed resource; however, high dietary inclusion of raw mulberry leaf impairs growth in carnivorous fish. Fermentation degrades anti-nutritional components and enhances nutrient availability, yet the dose-dependent effects and un...

Pangenome analyses reveal divergence and extensive introgression in two global corn pests

Introgression between closely related species can profoundly influence evolutionary trajectories, yet how genomic divergence interacts with introgression, especially in invasive hybridization, remains insufficiently understood. Structural variants (SVs), particularly chromosomal...

Population genomics reveals ginseng domestication and ginsenoside biosynthesis

Ginseng ( Panax ginseng ), a valuable medicinal plant, is cultivated for the bioactive ginsenosides with cardiovascular protective effects that are abundant in its roots. However, the genetic basis of its domestication and ginsenoside variation is not fully understood. In this st...

Biosynthesis and heterologous production of the α-agarofuran scaffold of Celangulin V from Celastrus angulatus

Celangulin V is a widely used biopesticide derived from Celastrus angulatus, and features antifeedant and insecticidal properties as a dihydro-β-agarofuran (DHβAF) sesquiterpenoid. Its biosynthesis remains largely unexplored. Here, we assemble a chromosome-level and haplotype-res...