AgriBio

Within-family effect of ancestry on complex traits in a Mexican population

Abstract Human populations differ in disease prevalence and phenotypes, but the extent to which differences are caused by genetic factors is unknown for most complex traits. Comparing phenotypic means across populations is confounded by environmental differences and using polygen...

Dissecting contributions of directional and balancing selection to trajectories of mitochondrial haplotype evolution in Drosophila melanogaster

Abstract Emerging evidence suggests mtDNA haplotypes contribute to fitness variation and local adaptation, with directional thermal selection and negative frequency-dependent selection shaping haplotype diversity. However, their interplay remains unexplored. We conducted experime...

Proliferative Sparganosis Due to Spirometra mansoni in a Dog: A Detailed Diagnostic Picture

ABSTRACT A young Blue Heeler presented for abdominal distension and weight gain, without a history of raw feeding or travel outside the western suburbs of Melbourne, Victoria, Australia. Abdominal ultrasound noted innumerable small anechoic oval cystic structures scattered throug...

Selective Packaging of miR‐22 and miR‐29 Orthologues into Extracellular Vesicles of the Porcine Whipworm Trichuris Suis

ABSTRACT Helminths modulate host immunity, and in this respect, the porcine whipworm Trichuris suis has been explored clinically as an immunotherapy for inflammatory diseases. T. suis secretes a complex mixture of excretory/secretory products (ESP), including extracellular vesicl...