Agir Pour les Maladies Chroniques

Efficacy and safety of temporary selective portal vein embolization before major hepatectomy (EMBORES): a phase 2 trial

Background Portal vein embolization (PVE) is routinely used before major hepatectomy to induce hypertrophy of the future liver remnant (FLR) and reduce post-hepatectomy liver failure. Conventional PVE relies on permanent embolic agents, resulting in irreversible portal occlusion,...

Non-linear mechanical field reconstruction coupling recurrent neural networks with physics-informed graph neural networks

Reconstructing local stress fields in heterogeneous microstructures under non-linear, history-dependent loading remains a major computational bottleneck in multi-scale simulations. We propose a coupled LSTM-GNN framework that links the temporal and spatial aspects of local stress...