Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail

Health-related interpretation of human biomonitoring results – new and updated human biomonitoring guidance values from PARC and HBM4EU

During the first three years of the Partnership for the Assessment of Risks from Chemicals (PARC), we derived health-based human biomonitoring guidance values (HBM-GVs) for 11 substances to enable the direct health-related interpretation of human biomonitoring (HBM) results. HBM-...

Multiplex species-specific real-time PCR assays for the detection of European Armillaria spp. and Desarmillaria spp. in different environmental substrates

Armillaria root rot, caused by basidiomycete fungi of the genera Armillaria and Desarmillaria , affects numerous agronomic crops and forest trees worldwide. In Europe, seven species have been described, namely Armillaria mellea , A. ostoyae , A. gallica , A. borealis , A. cepisti...

Estimation of the relative effectiveness and waning of the monovalent third dose of COVID-19 vaccine against hospital admission in France: a novel self-controlled case series analysis.

We present a novel application of the SCCS method for estimating the effectiveness and waning of the third dose of COVID-19 monovalent vaccine in France. We used data on individuals hospitalised for COVID-19 between September 2021 and February 2022 from the Système National des D...

Potential for real-time health and welfare monitoring of red fox (Vulpes vulpes) in experimental settings using implants

Monitoring and improving animal health and welfare is a pressing need. Technological advances are increasing our ability to do so in a range of settings but there are limited uses in experimental settings for less common model animals. Red foxes ( Vulpes vulpes ) are maintained b...

Quantifying uncertainty: a practical comparison of Bayesian and frequentist meta-analytic frameworks applied to lead exposure and children’s IQ

Abstract Background Uncertainty quantification is central to evidence synthesis for risk assessment and policy-making. Frequentist meta-analysis - currently predominant in epidemiology - quantifies uncertainty through confidence intervals, while Bayesian meta-analysis provides po...

Monitoring of Clostridium Botulinum in Poultry and Cattle Manure During Spreading Operations

Animal botulism mainly affects poultry and cattle, with risks of cross-contamination. This study aimed to evaluate Clostridium botulinum contamination in manure and soil following manure spreading on 13 clinically affected farms (10 cattle and three poultry) and 39 clinically una...

Contagious caprine pleuropneumonia: a review and gap analysis of its impact, epidemiology, pathogenesis, and control

Contagious caprine pleuropneumonia (CCPP), caused by Mycoplasma capricolum subsp. capripneumoniae ( Mccp ), remains one of the most important small ruminant diseases and a major transboundary disease. Although primarily affecting goats, infections have also been reported in sheep...

Discontools supplement Mycoplasma hyopneumoniae infections in pigs: update and knowledge gaps

This manuscript reviews current knowledge on Mycoplasma hyopneumoniae , the primary agent of enzootic pneumonia in pigs, integrating advances in epidemiology, pathogenesis, immunity, diagnostics, and control. The pathogen is globally endemic, with transmission driven mainly by di...