Agaplesion Diakonieklinikum Rotenburg

Using multi-trait polygenic scores to predict lithium responsiveness in patients with bipolar disorder

Background The predictive power of polygenic scores (PGSs) for lithium treatment response in bipolar disorder remains limited. Aims To enhance the prediction of lithium responsiveness by developing a multi-trait PGS (mt-PGS) combining genetic information from multiple phenotypes...

Upper- versus lower-extremity synovial sarcoma: distinct surgical pathways and postoperative morbidity in a 24-year cohort

Abstract Purpose Synovial sarcoma is a rare, late-relapsing soft-tissue sarcoma of the extremities. Whether anatomical location shapes the surgical treatment pathway, rather than prognosis alone, is unclear. We compared upper-extremity (UE) and lower-extremity (LE) tumors with re...

Introduction and validation of OSCAR—optimal stent choice algorithm

Abstract Purpose Standardization and international guidelines for stent size selection are lacking. In this study, we introduce and validate an artificial intelligence (AI)- and image processing-supported, modular software algorithm trained on a multicentric vascular segmentation...