Aga Khan University Hospital Nairobi

Immunohistochemistry vs Molecular Breast Cancer Subtyping Among African Populations

Importance Breast cancer subtyping based on immunohistochemistry (IHC) guides systemic therapy where gene expression profiling assays are unavailable, yet its validity against molecular reference standards remains poorly characterized in African populations, where laboratory infr...

The HEADSpAcE Data Center: An international data and biospecimen resource for head and neck cancer translational research

Head and neck cancer (HNC) comprises a heterogeneous group of malignancies with substantial variation in incidence, risk factors, and outcomes across populations. Existing studies are often limited by regional scope or lack integration of epidemiological, clinical, and molecular...

A qualitative study of the communication and information needs of parents of preterm Infants in a tertiary health facility in Northeast Nigeria

While the need for hospitalisation in preterm infants is a well-recognized source of stress and anxiety for most parents, the communication and informational needs of parents during this period remain vastly understudied in sub-Saharan Africa. This study aimed to investigate the...

Mapping the landscape: current status, challenges, and perspectives on scholarship of medical educationists in Pakistan

Medical Education Research (MER) is ruled by high-income countries, with restricted contribution from Low-and Middle-Income Countries (LMICs) like Pakistan; this is despite the mandatory requirements of Departments of Medical Education in every medical and dental college. This re...

Beta Thalassemia Carrier Detection in Individuals with Borderline Normal Hemoglobin A 2 Levels

Transfusion-dependent β-thalassemia is a significant public health challenge in many countries. Prevention through carrier detection enables counseling for at-risk couples and informed decision-making. Beta-thalassemia carriers are identified by elevated hemoglobin A2 levels (≥3....