Institution
Africa Centres for Disease Control and Prevention
Recent research
- Society & EconomicsOpen access
Abstract Background Malaria remains a severe public health crisis in Africa, causing 94% of global cases and 95% of deaths in 2023. While the rollout of the RTS, S/AS01 and R21/Matrix-M vaccines marks a historic shift, long-term public health success relies on adult acceptance pa...
- Health & MedicineOpen access
Background Many African countries have established national pharmacovigilance (PV) centers under their medicines regulatory authorities, but multiple barriers still limit system performance. Comprehensive, well-enforced PV regulations are often lacking, and the reporting culture...
- BiologyOpen access
Neuropsychiatry genetics in Africa
Across Africa, rising mental health needs coincide with rapid advances in genomics, digital health and continental policy reform. Yet research into the genetic, environmental and social determinants of neuropsychiatric illness remains sparse and underfunded. This review argues th...
- Health & MedicineOpen access
The 2026 Bundibugyo virus disease (BVD) outbreak in the DRC and Uganda raises urgent questions about the efficacy of existing Ebola virus (EBOV) monoclonal antibodies (mAbs) against Bundibugyo virus (BDBV). Here, we perform genomic and structural analyses of 44 BDBV sequences, in...
- Health & MedicineOpen access
Assessing the implementation of the disease surveillance and response strategy in Togo
The surveillance of infectious diseases has gained importance with the rise of (re)emerging pathogens and growing antimicrobial resistance. In many low- and middle-income countries (LMICs), surveillance systems remain insufficiently structured to support timely detection and resp...
- BiologyOpen access
Epidemic typhus, caused by Rickettsia prowazekii , remains a re-emerging public health concern in resource-limited and conflict-affected regions, underscoring the need for improved diagnostic tools. Although the citrate synthase (GltA) gene is widely used as a molecular diagnosti...
- Society & EconomicsOpen access
Development and validation of the personal recovery scale (ReConnect) for mental health in Ethiopia
Background: Socio-cultural context is crucial for conceptualising personal recovery in mental health, but existing measures are from Western, high-income countries. Aim: To develop and validate a mental health personal recovery measure for people with mental health conditions in...
- Climate & EnvironmentOpen access
{ "background": "Communal grazing reserves are a key rangeland management strategy in arid and semi-arid pastoral systems of the Horn of Africa, yet empirical evidence of their efficacy for biomass restoration remains limited and contested.", "purpose and objectives": "This study...
- Climate & EnvironmentOpen access
{ "background": "Communal grazing reserves are a key rangeland management strategy in arid and semi-arid pastoral systems of the Horn of Africa, yet empirical evidence of their efficacy for biomass restoration remains limited and contested.", "purpose and objectives": "This study...
- BiologyOpen access
Cholera remains a persistent public health challenge in Tanzania, with recurrent outbreaks across multiple regions overwhelming the health systems. Despite the ongoing surveillance to control the transmission, limited genomic characterization of circulating Vibrio cholerae strain...
- Health & MedicineOpen access
Digital health in pursuit of universal health coverage and equity challenges
The COVID-19 pandemic has accelerated the adoption of digital health technologies worldwide, positioning them as pivotal tools in the pursuit of universal health coverage (UHC). This commentary critically examines the dual potential of digital health: while innovations such as te...
- Health & MedicineOpen access
A common misconception is that Antimicrobial resistance (AMR) stems solely from poor treatment management in hospitals and weak health systems. AMR is, however, driven by a multitude of factors, including environmental stressors such as contamination from industrial, agricultural...
- Health & MedicineOpen access
Public Health Emergency Operations Centers (PHEOCs) are central to national health security systems, enabling coordinated preparedness, surveillance, and response to public health emergencies. However, their operationalization remains particularly challenging in fragile and confl...