Affiliated Hospital of Hebei University

Feasibility analysis of negative pressure wound therapy for odontogenic ascending necrotizing fasciitis: a single-center single-arm retrospective case series

Abstract Background Odontogenic ascending necrotizing fasciitis (ANF) is an extremely rare, rapidly progressive, and destructive craniomaxillofacial necrotizing soft tissue infection. Advanced surgical drainage is essential to improve cure rates, shorten the disease course, and a...

Single-cell transcriptomics uncovers HPV-driven immune evasion and establishes a TAB2-based prognostic signature in cervical cancer

Background Persistent human papillomavirus (HPV) infection is a key driver in cervical cancer, yet the molecular mechanisms linking HPV to immune escape remain incompletely understood. Methods We integrated single-cell RNA sequencing (scRNA-seq), bulk transcriptome, and clinical...

Association between the time window of rash recurrence and the risk of renal involvement within 6 months in children with immunoglobulin A vasculitis

Renal involvement is a major determinant of long-term outcome in childhood immunoglobulin A vasculitis (IgAV). We examined whether the timing of the initial rash recurrence was associated with renal involvement within 180 days, while accounting for temporal ordering, rash phenoty...

Association of dietary oxidative balance score, dietary inflammatory potential and fractures among adults aged ≥ 40 years in the United States in 1999-2018.

BACKGROUND AND OBJECTIVES: The Dietary Oxidative Balance Score (DOBS) and Dietary Inflammatory Index (DII) reflect dietary oxidative and inflammatory status. This study investigated their associations with the prevalence of wrist, hip, and spine fractures. METHODS AND STUDY DESIG...

Esketamine induces ferroptosis and suppresses immune evasion in lung adenocarcinoma cells via the hsa_circ_0022392/miR-548b-3p/MAP7 axis

Abstract Background Although Esketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, is widely used for anesthesia and analgesia and has shown anticancer activity, its effects on lung adenocarcinoma remain unclear. Circular RNAs have been implicated in the development and...