Affiliated Hospital of Guangdong Medical College Hospital

Identifying potential macrophage polarization-related causal genes in sepsis through multi-omics mendelian randomization analysis and experimental validation

The genetic associations between macrophage polarization-related genes (MPGs) and sepsis remain unclear. This study aimed to identify sepsis-associated MPGs. Based on blood-derived methylation quantitative trait loci (mQTL), expression QTL (eQTL), and protein QTL (pQTL) data for...