Adekunle Ajasin University

Computational design and optimization of Traditional Chinese Medicine compounds as potential inhibitors of Escherichia coli gyraseB

The increasing prevalence of antibiotic resistance among major pathogens poses a significant threat to public health, necessitating innovative control measures and novel antibacterial drugs. This study employs a computational design and lead optimization approach to discover new...

A selectivity-aware machine-learning workflow for prioritizing CDK2-biased kinase inhibitor candidates

Abstract Cyclin-dependent kinase 2 (CDK2) is a therapeutic target of interest, but selective inhibition remains challenging because ATP-competitive inhibitors often engage related CDK family members. Here, we developed a selectivity-aware computational workflow to prioritize CDK2...

Health Behaviour and Psychological Distress among Police Personnel in Ondo State, Nigeria: The Mediating Role of Physical Activity Status

ABSTRACT: Psychological distress is a growing occupational health concern among police personnel, particularly in contexts where officers are exposed to demanding work conditions, operational pressure, and limited wellness support. This study examined the relationship between hea...

Health Behaviour and Psychological Distress among Police Personnel in Ondo State, Nigeria: The Mediating Role of Physical Activity Status

ABSTRACT: Psychological distress is a growing occupational health concern among police personnel, particularly in contexts where officers are exposed to demanding work conditions, operational pressure, and limited wellness support. This study examined the relationship between hea...

Nigerian Salafi Discourse Corpus (NSDC): Construction, Methods, and Use

This paper documents the construction of the Nigerian Salafi Discourse Corpus (NSDC), a purpose-built corpus of 5,791 Facebook posts (2,485,963 words; 2,518,453 tagged tokens) published by Nigerian pages and profiles over a ten-year frame (2015-2025). The NSDC was assembled from...

Nigerian Salafi Discourse Corpus (NSDC): Construction, Methods, and Use

This paper documents the construction of the Nigerian Salafi Discourse Corpus (NSDC), a purpose-built corpus of 5,791 Facebook posts (2,485,963 words; 2,518,453 tagged tokens) published by Nigerian pages and profiles over a ten-year frame (2015-2025). The NSDC was assembled from...

Cruising on power: a critical stylistic study of gendered interaction in the parent-led matchmaking edition of Cruise

Insight into gender discourse requires examining both the ideologies embedded in interaction and the linguistic choices through which those ideologies are enacted. This study investigates how gendered ideologies are enacted and sustained through language in two episodes of the pa...

Reimagining research equity and beneficial community impact: reflections from the GSK Africa Open Lab inaugural cohort

Global health research continues to rely heavily on knowledge generated outside the regions that bear the greatest disease burden, reinforcing structural inequities in scientific leadership and innovation. The GlaxoSmithKline (GSK) Africa Open Lab (AOL) was established to address...