Institution
Academia Nacional de Medicina
Recent research
- Health & MedicineOpen access
Lipid-mediated GPR32 signaling reprograms macrophage metabolism to impair anti-tuberculous immunity
Abstract Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), has evolved strategies to evade innate immunity and establish persistent infection. However, the mechanisms by which M. tuberculosis reprograms human macrophage metabolism remain incompletely defined....
- Health & MedicineOpen access
Background: Decidualization alters the endometrial stromal cells (EnSC) secretome, allowing sterile inflammation associated with embryo implantation, but mechanisms that lead to alterations in this process are still unknown. We evaluated whether impaired IRE1α-mediated endoplasmi...
- Health & Medicine
Acquired hemophilia: insights from a multicenter real-life study in a middle-income country
Background Acquired hemophilia A (AHA) is a rare hemorrhagic disease with scarce published information from developing countries. Objectives The main objective was to describe the clinical manifestation and treatment, as well as laboratory characteristics of patients with AHA. Pa...