A. O. Ordine Mauriziano di Torino

Safety and Efficacy of Acute Normovolemic Hemodilution in Female Patients

Importance Female patients undergoing cardiac surgery have a higher transfusion burden, yet they remain underrepresented in randomized clinical trials. Although the ANH trial showed no significant reduction in the proportion of patients receiving allogeneic blood transfusions wit...

Beyond monospecificity in systemic lupus erythematosus: Emerging roles of bispecific and trispecific antibodies

Purpose Targeted biologic therapy has changed the management of systemic lupus erythematosus (SLE), including lupus nephritis (LN), but incomplete response, relapse, glucocorticoid dependence, and refractory organ disease remain common. This article discusses whether bispecific a...

Diagnostic Performance of Source-Recorded Food-Specific Prick-by-Prick Testing Against Oral Food Challenge Outcomes: A Challenge-Selected Single-Center Retrospective Study

Oral food challenge (OFC) is the reference standard for diagnosing IgE-mediated food allergy, whereas the performance of prick-by-prick testing (PbP) with native foods in routine care is uncertain. We retrospectively screened all food-specific OFC records from 2 January 2024 to 6...

Predicting the risk of dehydration and readmission among rectal cancer patients with ileostomy: a multicenter observational study

Abstract Dehydration is a frequent complication among rectal cancer patients after ileostomy, often resulting in hospital readmission. The Dehydration Readmission after Ileostomy Prediction (DRIP) score was used to identify patients at risk of dehydration-related readmission. The...

Timing of PCI in Patients Undergoing Transcatheter Aortic-Valve Implantation

BackgroundApproximately one half of patients undergoing transcatheter aortic-valve implantation (TAVI) have concomitant coronary artery disease. Although percutaneous coronary intervention (PCI) is often performed before TAVI, the preferred treatment strategy has not been establi...

Hallux Valgus, Not Hallux Abductus Valgus: A Short Report on Historical and Anatomical Terminology

Background: This short report argues that the term “hallux abductus valgus” is anatomically inconsistent and should be replaced by “hallux valgus.” Hallux valgus describes a lateral deviation of the great toe with a medial deviation of the first metatarsal. Although the deformity...

Incidence and Risk Factors of Unplanned Emergency Department Transfers From Italian Nursing Homes: A Prospective Multicentre Cohort Study

ABSTRACT Aim To estimate the incidence of unplanned transfers to the emergency department among nursing home residents and to identify resident and organizational factors associated with transfer risk. Design A 12‐month prospective multicentre dynamic cohort study. Methods The st...

Real‐world outcomes of venetoclax plus hypomethylating agents in unfit acute myeloid leukaemia: Results of the GIMEMA AML2320 trial

Summary Venetoclax (VEN) plus hypomethylating agents (HMAs) represents the standard of care for newly diagnosed acute myeloid leukaemia (AML) patients unfit for intensive chemotherapy, but prospective real‐world observational data outside randomized clinical trials remain limited...