5T Torino (Italy)

Integrated internal standard volumetric dried blood microsampling for the quantification of phosphatidylethanol 16:0/18:1

Phosphatidylethanol 16:0/18:1 (PEth) is a direct biomarker of alcohol consumption, formed in red blood cell membrane in the presence of ethanol. Concentrations of 20 ng/mL and 200 ng/mL have been proposed as cut-offs to distinguish abstinence or low alcohol consumption from moder...

Brief communication: Shared parameterisation for estimating snow water equivalent through cosmic ray neutron sensors in the Italian Alps

Abstract. We present a novel approach based on leveraging a shared parameterisation to derive snow water equivalent (SWE) with cosmic ray neutron sensing (CRNS) probes. The network comprises 26 sites (1422–2901 ma.s.l.) in the Italian Alps. The parameterisation was defined by fit...

Cemiplimab in cutaneous squamous cell carcinoma: a longer follow‐up study focusing on the late toxicities

Summary Background and Objectives Cemiplimab was the first systemic therapy approved for advanced cutaneous squamous cell carcinoma (cSCC). Patients and Methods We report findings from the Italian early access program cohort, comprising 134 patients treated with cemiplimab, with...

Availability and representativeness of freshwater macroinvertebrate data to enable Europe-wide assessment of biodiversity trends

Freshwater ecosystems, though covering less than 1% of Earth's surface, harbor around 10% of all species. Pressures like pollution, water extraction, and habitat loss can exhibit complex interactions in their effects on freshwater biodiversity. Understanding the effects of these...

A factorial multi‐layer analysis reveals non‐additive sulfur–iron interactions shaping metabolic and transcriptional responses in durum wheat

Summary Reciprocal iron–sulfur regulation in durum wheat converges on a few metabolic hubs that integrate nutrient status with plant growth and performance. Iron and sulfur availabilities were factorially modulated in hydroponically grown wheat to establish how each nutrient and...