117th Hospital of People's Liberation Army

Development of ferroptosis-related prognostic signature for lung adenocarcinoma and association of fibroblast-enriched RGS4 with favorable prognosis

Lung adenocarcinoma (LUAD) is characterized by high incidence and low survival rate. The molecular network of ferroptosis in lung adenocarcinoma requires further investigation, and this study aims to develop a ferroptosis-related prognostic model and identify the potential biomar...

A Macromolecule npEt20 Exerts Broad-Spectrum Synergistic Effects With Meropenem Against Multidrug-Resistant Gram-Negative Pathogens

Background: The widespread emergence of multidrug-resistant (MDR) Gram-negative bacteria severely compromises the clinical efficacy of carbapenem antibiotics, leading to refractory nosocomial infections. Novel antibacterial agents that can reverse carbapenem resistance are urgent...

Continuous glycemic phenotype derived from latent class mixed models predicts 28-day mortality after traumatic brain injury: a two-cohort study

Abstract Acute stress hyperglycemia is common after traumatic brain injury (TBI) and is associated with adverse outcomes. However, the prognostic value of longitudinal glucose trajectories during the early ICU stay remains poorly characterized, and whether post-TBI glycemic dynam...

Efficacy and safety of combined intravenous and topical tranexamic acid in primary total hip arthroplasty: a meta‑analysis and systematic review of randomized controlled trials

Both intravenous (IV) and topical tranexamic acid (TXA) reduce bleeding in total hip arthroplasty (THA), but the added benefit of combining the two routes and the potential modifying effect of topical dose remain unclear. We performed a systematic review and meta‑analysis of RCTs...

Platelet count combined with Child-Turcotte-Pugh score for predicting rebleeding in cirrhotic patients with esophagogastric variceal bleeding

To investigate the predictive value of platelet count (PLT) combined with the Child-Turcotte-Pugh (CTP) score for rebleeding in cirrhotic patients with esophagogastric variceal bleeding (EGVB). This single-center retrospective study included 332 eligible patients selected from 37...