1 Military Clinical Hospital with Outpatient Clinic

Childhood Diet, Gut Microbiota and Early Cardiovascular Risk: A Narrative Review

Childhood dietary patterns play a key role in shaping early cardiometabolic risk through effects on adiposity, lipid metabolism, inflammation, insulin sensitivity, and gut microbiota composition. Evidence indicates that atherosclerotic processes begin in early life and are strong...

Plasma neurofilament light chain in type 2 diabetes: Associations with diabetic peripheral neuropathy, age, and renal function in a pilot cross-sectional study

Background Diabetic peripheral neuropathy (DPN) is a common complication of type 2 diabetes mellitus (T2DM). Neurofilament light chain (NfL) is a circulating marker of neuroaxonal injury, but its interpretation may be influenced by age and renal function. Objective To evaluate th...

Differential expression of TGF-β1, TGF-β2, and TGF-β3 across WHO grades in meningioma: convergent evidence from mRNA, methylation, miRNA, and protein analysis

Meningiomas show biological heterogeneity not captured by WHO grading alone. TGF-β signaling has been implicated in meningioma pathobiology, yet a systematic, grade-stratified, isoform-resolved characterization of TGF-β1, TGF-β2, and TGF-β3 across transcriptional, epigenetic, pos...

Lipoprotein(a) as a Cardiovascular Risk Factor: Clinical Significance and Therapeutic Perspectives

Lipoprotein(a) (Lp(a)) is an elusive yet powerful cardiovascular risk factor, largely independent of LDL cholesterol. Elevated Lp(a) increases the risk of coronary artery disease, stroke, peripheral arterial disease, calcific aortic valve disease, heart failure, and abdominal aor...