Zi’an Tang

MC-NODE: A Mechanism-Decomposed Neural Differential Model for PLGA Microsphere Drug Release Prediction and Attribution

Background/Objectives: Poly(lactide-co-glycolide) (PLGA) microspheres support long-acting drug delivery, but their release profiles are difficult to predict because burst release, diffusion, polymer degradation, and formulation-dependent effects interact across multiple time scal...