Zhong‐Yan Cao

Synthesis of Pyrroloquinazolinones via Base-Promoted Domino Reaction of 7-Vinylindoles with In Situ Formed Isocyanates from Dioxazolones

Abstract Herein, we report a novel base-promoted domino reaction between 7-vinylindoles and dioxazolones, enabling the efficient one-pot synthesis of pyrroloquinazolinone scaffolds in moderate to excellent yields (up to 95%). This transition-metal-free protocol employs readily av...

Stereodivergent Synthesis of C -Glycosides from Glycals by Ni-Catalyzed Cross-Hydrocarbonylation of Alkenes

Abstract C-Glycosides always significantly improve the physicochemical properties and pharmacokinetic characteristics of the native O- and N-glycosides and are one of the most powerful strategies for carbohydrate-based drug discovery. However, direct access to C-glycosides with c...

Recent advances in TPT-based crystalline hybrid materials: from structural design to functional applications

2,4,6-Tri(4-pyridyl)-1,3,5-triazine (TPT), featuring a rigid C 3 -symmetric π-conjugated skeleton, an electron-deficient triazine core, and three pyridyl coordination sites, has emerged as a powerful building block for the construction of crystalline hybrid materials. The unique...