Zhongjie Ji

Dual-targeted bioengineered bacterial extracellular vesicles ameliorate senile osteoporosis via SAE1-mediated NAT10 SUMOylation and ac4C-dependent glycolysis

Senile osteoporosis (SOP) is an age-related skeletal disease characterized by progressive bone loss and the deterioration of bone microarchitecture. Promoting the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) is a potential strategy for SOP intervention...