Zhizhun Mo

CD147 exacerbates ischemic brain injury and disrupts Wnt/β-catenin signaling and blood-brain barrier integrity

Abstract Ischemic stroke is a leading cause of death and disability, with limited therapies beyond reperfusion. CD147 (Basigin), upregulated after cerebral ischemia, participates in neuroinflammation, however, its precise contributions to blood-brain barrier (BBB) disruption and...