Zhiyuan Jian

Aptamer-functionalized exosomes co-delivering miR-934 inhibitor and gemcitabine for targeted pancreatic cancer therapy

Pancreatic cancer remains a malignancy with limited treatment efficacy and high resistance to chemotherapy. miR-934 was identified as an oncogenic miRNA significantly upregulated in pancreatic cancer, promoting tumor progression, epithelial-mesenchymal transition (EMT), and chemo...