Zhixin Qiu

Lysosomal homeostasis maintained by DCPS-mediated SLC4A7 splicing confers dependency in glioblastoma stem cells

Abstract Glioblastoma (GBM) is an aggressive brain tumor driven by GBM stem cells (GSCs), which lack therapeutic targets. Here, we identify RNA decapping enzyme DCPS as an essential regulator of GSC maintenance and GBM progression. Epigenetically regulated DCPS expression levels...

Differentiating Nontuberculous Mycobacterial Lung Disease from Pulmonary Tuberculosis: A Retrospective Study on Clinical Features and a Diagnostic Model

Background: Nontuberculous mycobacterial pulmonary disease (NTM-PD) and pulmonary tuberculosis (PTB) present with similar clinical and radiological features, frequently leading to misdiagnosis. This study aimed to compare NTM-PD with extrapulmonary NTM disease (ENTM) and PTB and...