Zhiming Shao

Exploratory integration of spatial transcriptomics and MRI phenotypes to characterize metastasis-associated microenvironmental features in ipsilateral breast tumor recurrence

Ipsilateral breast tumor recurrence (IBTR) presents a critical clinical challenge, as it is strongly associated with a high risk of subsequent distant metastasis, the primary cause of mortality. Although the spatial organization of the tumor microenvironment (TME) may contribute...