Zhijuan Duan

Nanopipette Sensing of APE1 Activity via Enzymatic Recycling and DNA Tetrahedron−Streptavidin Reporting: Profiling in Cancer Diagnostics, Oxidative Stress, and Cell Cycle

Abstract Apurinic/apyrimidinic endonuclease 1 (APE1) is a clinical biomarker whose small molecular size hinders direct detection by conventional nanopores (30 nm). Here, we report a nanopipette platform integrating APE1-driven enzymatic recycling amplification with DNA tetrahedro...