Zhi Zhang

Corticothalamic circuits drive voluntary physical exercise-mediated relief of surgery-induced negative emotions in mice

Surgery-induced negative emotions (SINE), such as fear and anxiety, are common clinically and hinder postoperative recovery. Although physical exercise is known to modulate various affective disorders, the underlying mechanisms by which voluntary physical exercise alleviates SINE...

Targeted‐Penetrating Biomimetic Hybrid Transfersomes for Enhanced Transdermal Gene Transfection in Hypertrophic Scar Therapy

ABSTRACT Hypertrophic scar (HS) is a recurrent and inflammatory dermal fibrotic disorder, characterized by abnormal fibroblast proliferation and excessive extracellular matrix (ECM) deposition. Affecting over 310 million patients worldwide, while effective strategies to halt prog...

Effect of thoracic paravertebral block with liposomal bupivacaine on quality of recovery after video-assisted thoracic surgery: a randomized controlled trial

Abstract Background The effect of thoracic paravertebral block with liposomal bupivacaine on recovery after video-assisted thoracic surgery remains uncertain. Methods This single-centre, double-blind, randomized controlled trial enrolled ninety adults aged 18 to 65 years who were...