Zhen‐Zhu Xue

Dynamic Changes and Diagnostic Value of Plasma Tryptophan and Its Metabolites in Different Stages of Hepatic Encephalopathy Detected by Ultra‐Performance Liquid Chromatography–Tandem Mass Spectrometry

ABSTRACT Hepatic encephalopathy (HE) is a severe neuropsychiatric complication of liver disease. Early diagnosis remains challenging due to insidious onset and lack of stage‐specific biomarkers. Tryptophan (TRP) metabolism is closely linked to the gut–liver–brain axis and is dysr...