Zhengshou Zhang

Single-cell and spatial transcriptomics reveal glycolytic remodeling and ENO1-associated metabolic vulnerability in hepatoblastoma

Hepatoblastoma (HB) is the most common malignant liver tumor in children; however, the contribution of glycolytic metabolic reprogramming to HB development and progression remains incompletely characterized. We integrated single-cell RNA sequencing and spatial transcriptomic data...