Zhengmao Zhu

Hypoxia combined with vitamin C and N-acetylcysteine attenuates telomere shortening and replicative senescence in human umbilical cord mesenchymal stem cells

Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) are promising candidates for regenerative medicine; however, prolonged in vitro expansion promotes oxidative stress, replicative senescence, functional deterioration, and telomere attrition. This study evaluated wheth...