Zhen Wang

AI-Driven precision targeted therapy for EGFR-mutant non-small cell lung cancer: From therapeutic evolution and resistance mechanisms to intelligent decision systems

ObjectiveTo critically review the current pharmacologic treatment landscape for epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC), focusing on clinical pharmacology, therapeutic evolution, and emerging challenges of EGFR-targeted therapies.Data Sou...

LncRNA GAS6-AS1 promotes ischemic stroke injury through miR-370-3p/TFRC-mediated ferroptosis and disruption of Nrf2/ARE antioxidant responses

Ischemic stroke induces severe neuronal injury after ischemia/reperfusion (I/R), with oxidative disturbance and ferroptotic death emerging as critical contributors. Although GAS6-AS1 has been associated with ischemic stroke progression, the molecular mechanisms underlying its fun...