Zhaocheng Liu

The Alkaline Non-Structural Protein–Ferritin–TRPV1 Axis: A Unified Chemical Model for Fever, Viral Latency, and HIV Associated CD4 Exhaustion

Current fever models attribute hypothalamic set‑point elevation to prostaglandin E2, yet they fail to explain the incubation period, ferroptosis, or the perplexing CD4 depletion in HIV patients under suppressive antiretroviral therapy. We propose a fundamentally different framewo...

The Alkaline Non Structural Protein–Ferritin–TRPV1 Axis: A Unified Chemical Model for Fever, Viral Latency, and HIV Associated CD4 Exhaustion

AbstractCurrent fever models attribute hypothalamic set‑point elevation to prostaglandin E2, yet they fail to explain the incubation period, ferroptosis, or the perplexing CD4 depletion in HIV patients under suppressive antiretroviral therapy. We propose a fundamentally different...