Zhang Zhang

Interlayer Bonding through Olefin Metathesis in 3D-Printed Poly(dicyclopentadiene) Thermosets

Abstract The direct ink writing (DIW) of thermosetting polymers is fundamentally constrained by weak interlayer bonding, leading to mechanical anisotropy and limiting their use in structural applications. Existing strategies to mitigate this challenge typically rely on thermal po...

Discovery of Arginine-Reactive Covalent Kinase Inhibitors Overcoming Clinical Drug Resistance

Abstract Covalent kinase inhibitors (CKIs) serve as potent therapeutics, yet their development largely depends on conserved cysteine residues. Many kinases lack accessible cysteines or develop resistance mutations at these sites, limiting clinical utility. To diversify targetable...