Zhan-Guo Gao

Structural insight into the activation of adenosine A2AR/A2BR by the dual-agonist MRS3997

Abstract A 1 R, A 2A R, A 2B R, and A 3 R adenosine receptors comprise a G protein-coupled receptor (GPCR) subfamily that regulates many bodily processes. Subtype-selective agonists potentially treat inflammatory and ischemic conditions. The dual A 2A R/A 2B R agonist MRS3997 pro...