Zhan Chen

Mechanistic roles of the NLRP3–caspase-1 signaling axis in atherosclerosis: pyroptosis, interaction networks, and therapeutic targets

Atherosclerosis (AS) is a chronic inflammatory condition marked by lipid and immune cell accumulation in arteries, leading to plaque formation and vascular dysfunction. The nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammaso...